Retinopathy of Prematurity

ROP is a disease that affects premature infants. In the womb, the retinal blood vessels grow late in pregnancy. When a baby is born very early, this normal growth is interrupted. After birth, abnormal, fragile blood vessels may begin to grow in the retina. These vessels can leak and scar, potentially pulling the retina off (detachment).

ROP is a disease that affects premature infants. In the womb, the retinal blood vessels grow late in pregnancy. When a baby is born very early, this normal growth is interrupted. After birth, abnormal, fragile blood vessels may begin to grow in the retina. These vessels can leak and scar, potentially pulling the retina off (detachment).

Symptoms

Parents cannot see signs of ROP. There are no obvious external changes to a baby's eyes in the early stages. This is why mandatory screening exams for at-risk infants are so vital.

Diagnosis

All babies born before 30 weeks gestation or weighing less than 1500 grams (3.3 lbs) are screened. A pediatric retinal specialist will examine the baby's retina using a special light and lens after dilating the eyes using drops. They may also use a wide-field retinal camera to document the findings. The disease is graded by its severity, location, and whether the blood vessels are abnormally twisted ("plus disease").

Treatments

Many mild cases improve on their own. For more severe ROP, treatment is highly effective at preventing blindness: Laser Therapy: The standard treatment, where a laser is used to treat the peripheral retina and stop abnormal growth. Anti-VEGF Injections: A medication may be injected into the eye to block the signal causing abnormal vessels. Surgery: If the retina detaches, complex surgeries (vitrectomy or scleral buckle) may be attempted to reattach it.

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