Intravitreal injection

Direct injection of medication into the vitreous (the eye's gel-like substance) is used to treat vascular and inflammatory diseases of the retina and macula. Common injectable drugs include anti-VEGF agents (such as Avastin, Eylea) to reduce abnormal blood vessel growth and retinal edema, and corticosteroids (such as triamcinolone, Ozurdex) to suppress and control inflammation.

Direct injection of medication into the vitreous (the eye's gel-like substance) is used to treat vascular and inflammatory diseases of the retina and macula. Common injectable drugs include anti-VEGF agents (such as Avastin, Eylea) to reduce abnormal blood vessel growth and retinal edema, and corticosteroids (such as triamcinolone, Ozurdex) to suppress and control inflammation.

Before procedure

Fasting is usually not required for performing intravitreal injections. Immediately prior to the injection, a generous amount of topical anesthetic and antiseptic (Betadine) drops are applied to minimize the risk of intraocular infection.

After procedure

The ophthalmologist may prescribe antibiotic and anti-inflammatory eye drops for several days following the injection. The patient must avoid rubbing the eye. Small spots of medication or blood may be seen floating in the visual field, which typically absorb over time. Generally, the patient can quickly resume normal daily activities.

Complication and alarm signs

Endophthalmitis (intraocular infection) is a significant complication characterized by severe pain, sudden vision loss, progressive redness, and discharge, requiring emergency medical attention. A sudden increase in floaters, seeing flashes of light, or shadows (curtains) may indicate a serious condition such as retinal detachment or hemorrhage. Increased intraocular pressure may also occur.

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